Post doc on socially transferred materials

Descrizione

Post doc on socially transferred materials Sintesi in italiano (traduzione automatica): Il progetto finanziato dall'HFSP si concentra sui Materiali Socialmente Trasferiti (STM), un campo emergente della scienza. La sede del lavoro è in un team multidisciplinare che include ricercatori in diverse località, tra cui Cambridge, Regno Unito, e San José, Costa Rica. Le mansioni principali includono l'affinamento della tecnica di imaging di massa per analizzare materiali provenienti da organismi non modello, la visualizzazione di STMs e dei loro recettori in tessuti specifici, e la conduzione di bio-assay su lumache d'acqua dolce. È richiesta esperienza in spettrometria di massa,ibridazione in situ e bioinformatica. È preferibile un dottorato in biologia, biotecnologie o discipline affini. The HFSP-funded project revolves around the concept of Socially Transferred Materials (STMs), which was defined a few years ago as an emerging new field in science: Across animals, organisms have repeatedly and convergently evolved ways to transfer materials between bodies that manipulate or support receiver physiology, fertility, or behaviour. Think of milk, seminal fluid, eggs, mucus, and regurgitates. Despite their ecological importance and applied potential, understanding of the molecular mechanisms underlying STM function across evolutionary distant lineages is lacking. This project aims to combine a multitude of -omics and imaging techniques as well as functional studies to work towards deep, large-scale analyses of STM evolution and action. The focus will lie on a range of arthropods, molluscs, and chordates, with the aim to uncover universal STM design principles as well as lineage-specific variants. Your duties Using your experience and enthusiasm for mass spec, in-situ hybridisation and bioinformatics, you will start by refining the mass spec imaging technique for work on material from non-model organisms. This technique will subsequently be used to visualise candidate STMs, and their receptors, in specific tissues of a selected set of focal species. The most promising candidate proteins will be applied in bio-assays using freshwater snails to test their bioactivity. These candidates will emerge from collaboration among the three post-docs on the project and will require well-organised teamwork across countries and continents. Hence, you will become part of a new, multidisciplinary team together with two other post-docs (one ant-leaning and hosted by Adria LeBoeuf in Cambridge, UK and one frog-leaning and hosted by Jenny Stynoski in San José, Costa Rica). The results are expected to lead to shared multi-author publications in high-quality scientific journals, where efforts from the three post-docs come together in large-scale analyses of STMs. In addition, the methods development, bio-assay testing and single species findings are expected to be published by smaller author teams. Annuncio in inglese. Fonte: Euraxess (Commissione europea).