post-doctoral researcher (M/F)

Descrizione

post-doctoral researcher (M/F) Sintesi in italiano (traduzione automatica): È disponibile una posizione post-dottorato di 18 mesi nel team di ricerca 'Integrità del genoma durante la replicazione del DNA' presso l'Istituto di Genetica Umana (IGH, CNRS – Università di Montpellier, Francia). Il progetto si propone di caratterizzare l'organizzazione tridimensionale del genoma durante la replicazione del DNA nel lievito a gemmazione Saccharomyces cerevisiae. Il candidato selezionato utilizzerà approcci genomici ad alta capacità, tra cui ChIP-seq e Hi-C, per indagare l'interazione tra replicazione del DNA e architettura del genoma. Sono richieste competenze in biologia molecolare avanzata, ingegneria genetica e bioinformatica. È preferibile una laurea in Biologia o un campo correlato. Il ricercatore lavorerà sotto la supervisione di Armelle Lengronne e collaborerà con un team di circa 18 membri. An 18-month postdoctoral position is available in the "Genome Integrity during DNA Replication" research team at the Institute of Human Genetics (IGH, CNRS – University of Montpellier, France). The project aims to characterize the three-dimensional organization of the genome during DNA replication in the budding yeast Saccharomyces cerevisiae. The successful candidate will use high-throughput genomic approaches, including ChIP-seq and Hi-C, to investigate the interplay between DNA replication and genome architecture. The successful candidate will be expected to: Implement quantitative genomics approaches, including ChIP-seq and Hi-C, to investigate genome organization during DNA replication. Perform advanced molecular biology experiments, including genetic engineering and cultivation of Saccharomyces cerevisiae, preparation of DNA libraries for high-throughput sequencing, and optimization of experimental protocols. Apply bioinformatics tools for the processing, integration, and interpretation of high-throughput sequencing data, particularly ChIP-seq and Hi-C datasets. Analyze, interpret, and present research findings through high-quality figures, reports, and scientific presentations. Ensure the traceability and reproducibility of experimental work by maintaining detailed protocols and effectively communicating experimental data within the research team. The recruited postdoctoral researcher will join the Institute of Human Genetics (IGH, UMR9002, CNRS) in Montpellier, France. The institute comprises approximately 220 staff members distributed across 21 research teams working on genome dynamics, developmental genetics, and human diseases. The successful candidate will join the "Genome Integrity during DNA Replication" team, headed by Philippe Pasero, which includes around 18 members. More specifically, they will work on the project "Genome organization during DNA replication" under the supervision of Armelle Lengronne. Annuncio in inglese. Fonte: Euraxess (Commissione europea).