Doctoral Researcher (Environmental Chemicals and Endometriosis)

Descrizione

Doctoral Researcher (Environmental Chemicals and Endometriosis) Sintesi in italiano (traduzione automatica): L'Università di Tampere e l'Università di Scienze Applicate di Tampere cercano un Ricercatore Dottorale nel campo della tossicologia molecolare e della salute riproduttiva femminile. La posizione è a tempo pieno e ha una durata fissa di 4 anni, con sede presso il Kauppi Campus. Il candidato selezionato contribuirà al progetto EIRIS, che studia come i prodotti chimici che alterano il sistema endocrino possano contribuire all'endometriosi. Le mansioni principali includono la raccolta di evidenze, esperimenti in laboratorio e analisi dei dati. È richiesta una laurea in scienze della vita e una forte motivazione per la ricerca. Sarà fornita formazione specifica in tossicologia e opportunità di collaborazioni internazionali. Tampere University and Tampere University of Applied Sciences create a unique environment for multidisciplinary, inspirational and high-impact research and education. Our university community has its competitive edges in technology, health and society. www.tuni.fi/en . We are looking for a Doctoral Researcher in the field of molecular toxicology, systems biology, and women’s reproductive health . The position is full-time and will be filled for a fixed-term period of 4 years. The workplace is located at Kauppi Campus, Tampere University. The Faculty of Medicine and Health Technology (MET) is dedicated to pursuing world-class research and delivering high-quality education in the fields of biomedical engineering, biotechnology, medicine and health technology. We conduct internationally acclaimed basic and applied research. The position is hosted by the Mechanistic and Applied Toxicology (MAT) research group, a newly established group led by Dr Alexandra Schaffert. MAT develops next-generation, animal testing-free approaches to chemical safety, combining molecular biology, proteomics and computational methods to understand how chemicals affect human health, with a particular focus on endocrine disruption and women’s reproductive health. Job description We are seeking a highly motivated Doctoral Researcher to join EIRIS , a research project investigating how endocrine-disrupting chemicals contribute to endometriosis, a common, painful and historically under-researched condition affecting roughly one in ten women. Despite widespread environmental exposure to endocrine disruptive chemicals, their role in female reproductive disease remains poorly understood. EIRIS is among the first to address this question systematically, building the first comprehensive mechanistic map of how everyday chemical exposures may promote the disease. The project sits at the intersection of environmental health, women’s health and next-generation, animal-free toxicology. Tasks As Doctoral Researcher, you will play a central role in EIRIS, contributing to both the experimental and data-driven parts of the project. Your work will combine structured evidence synthesis, computational/data-oriented analysis, and hands-on wet-lab experiments: Systematically collecting and curating published evidence on chemical effects in endometriosis into a structured, openly available knowledge base using systematic evidence mapping and language model-assisted approaches Establishing human endometrial cell models and carrying out controlled chemical exposure experiments Generating proteomic and secretomic samples (LC-MS/MS) and performing in vitro assays Biological interpretation of omics, pathway, clustering and network-analysis results Presenting results at conferences, attending trainings, and contributing to publications You will be fully trained in all relevant methods and will undertake short research visits to partner laboratories within Finland and abroad. You will work closely with a computational postdoctoral researcher and an international network of collaborators across toxicology, bioinformatics and women’s health. Prior knowledge in toxicology is welcome but not required, we will provide the toxicological training. What matters most is a solid background in the life sciences, curiosity, careful working habits, willingness to work across both hands-on wet-lab experiments and data-oriented/computational approaches, and a strong interest in a societally important and emerging research question. The selected candidate will be able to focus on their doctoral research full-time and will receive dedicated supervision and mentoring, while being encouraged to develop scientific independence and implement new ideas as part of a supportive, positive and multidisciplinary research environment at the MET faculty. In addition to the doctoral dissertation, the duties of a doctoral researcher include participation in education or other faculty tasks that support your studies. Annuncio in inglese. Fonte: Euraxess (Commissione europea).